Wednesday 23 January 2019

Adna's Lab Tutorial Video #1 - 'The Buffer/Enzyme combination'



Remember the Serious Games I created with my company SciBoard Games for anyone to learn about DNA manipulation and genetics? Well, it's fully available for free by clicking on the link at the very bottom of this post. Starting today and for the coming month I will be posting a series of tutorials for you to learn how to play this simple, easy and extremely realistic and enticing game:

The game started as usual with the ATG codon (methionine at the initiation site) setting the mood for the starting player (0:39).
Then another powerful card, the agarose gel to 'extract' and add additional bases to one's deck (1:46).
A tremendously clever strategy applied with the contamination of the opponent's chain by playing a bit of RNA (uracil card) in the mixture (
2:29)!!!
How would the affected player get rid of that? Well he/she was also clever and counter-attacked with the deletion card (
2:50) removing the contamination quite quickly; but it's not always like that as the number of cards of each type are limited and holding a proper strategy is crucial.
It can be tricky for a player to get rid of contamination in due course whilst the opponent's chain grow longer and longer. It is important to constantly be checking the enzymes cards (1:!8) (
2:04) (02:43) (03:35) for recognising cutting sequences in the opponent's chain.
Also very relevant to check what buffers are available as they need to match the enzyme colour to use. This is all about strategy. This time one of the players got caught up in that blue buffer, the only one he/she had whilst not blue enzyme was readily available (
03:53) (04:54).
When the chains were approximately the same length and the finish line was so close, the losing player did not have any good reactions or enzymes to play, then resorting to just adding more bases to his/her own chain (
05:09).
It wasn't enough as the opponent simply walked his/her way to the finish line just by playing a few cards more (
05:18) and winning the game with few points but the victory satisfaction.
Remember, the more bases, reactions and enzymes you use, the more points you get. These don't even have to be played on your own chain! The great thing about Adna's lab is that it isn't about luck, it is about acquired knowledge and trying possible combinations to get points, even if you have to cut your own chain! Now let us know if you found this tutorial video helpful.


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