Showing posts with label Detoxifying Notes. Show all posts
Showing posts with label Detoxifying Notes. Show all posts

Monday, 3 January 2022

A genuine thank you and farewell - this is the end of The Toxicologist Today


Since I was a child I have cultivated a few great passions in life, passions that overtime grew into professional objectives or intense hobbies. Some of these passions became a reality at adulthood, and some other ones simply didn't happen. No one is to blame, life is never linear and we, ourselves, are emotional roller-coasters who respond to time and experiences in different manners throughout our path. At some point when I was about eight years old I knew I wanted to be a medical doctor, a passion I had for taking care of people and shape their health to improved levels. By the age of 16 I really felt deeply connected with endocrinology and felt that I would be a great fit in said medical area. None of this became a reality because ... I simply don't know why, but I have my suspicions. Overall, it wasn't to happen. But the passion is still there; the motivation? Not so much!

I also, as a child, wished I was a writer published globally, not for the sake of money, I can assure you that regardless of how you might consider my ego, but for the sake of having so much to say about life, and at that time, so few people interested in what I thought. I wrote my first book, a novel about depression and misfortune at the age of 16 - "Gray Mosquitoes - Tragic fable of a suicidal" - was the name of that creation. The book did well in a national literature competition in Portugal and prompted me to keep writing. Writing for me was natural, writing for me was energetic, writing for me was deeply and utterly necessary to cleanse and integrate, accommodating all those feelings and observations into a structured analytical perspective. After that first novel several other followed, "Nayf" told the story of a fatherless adolescent with no emotional structure at all and who pushed back any external attempt of others to help him; and "As long as the world lasts" compiled numerous lyrics written for my personal music projects, like the band I had started back in 1995 named "Salem's Voice". 

Music is still one of my passions as it was in the past and as it as always been. I play bass and guitar but I am not a pro, I just like the way it makes me feel, it transports me to realities where the weight of the days simply isn't there anymore and for a few minutes I can evade from a deeply disturbed planet to a conceptualisation of whatever I want, based on what I am playing or listening to. Music does indeed heal, people know it, it is an accessible emotional 'psychotropic' with very few side effects. For me, from the moment I started playing some rubbish chords until the time I became the lead singer of my own band, music made perfect sense, but I always saw it as a positive therapeutic distraction from a convulsive meaningless world, and still today I hold the very same perspective on music-and-me.

My deep self wanted a better world for all, especially for those who experienced in life the same trajectory that I have had. I was born in an African country deeply devastated by civil war, moved to Europe, my family took a lot of time to base themselves in a region which made me experience 9 schools/nurseries (very much geographically distant) before joining university; and making friends became a hardship. And when you don't have the skills to make friends that easy, simply because you don't have the stability and they don't have the capacity to understand it and be an active part of your journey (empathy is a rarity in growing adolescents - believe me), you become isolated, misunderstood, atypical and mildly unwanted around the hordes of teenagers who are themselves trying to make sense of the world they were given to. This is when reading, one of my passions and that I recall having emerged in my life from the moment I started primary school, became ever so important. I have always been completely mad about compulsive reading, trying to intake all knowledge possible about so many different things. And this is one of the aspects that really characterises me, the capacity to show interest and discuss so many different topics - it has helped me connect with people I have very little in common with, and it has helped me adapt to the different urban tribes a lot better. 

I always read and read and read as much as possible. As a child I consumed the books of a library near my house, furiously, but at home the books I could find never triggered any interest as the topics were pretty much related to my parents' professional occupations, and those were never a passion of mine. I have always been a kid who was never compelled to follow his parents' professional routes; never liked it, never appealed to me. In that limitation (struggling to find something good to read) I turned to the community library, it was free, the range of books was much larger, but the topics were institutionalised and that was vastly boring. I have always been a person with enormous inner discomfort in relation to social injustice and inequity. I share it not to obtain any type of societal approval but to open up space for the external understanding that said attitude really shaped my years to come and the way I still operate to date. The need for information on more obscure realities, knowing the technicalities of the different things that were taking place around us and the different visions we could lay upon these systems drove me to many interesting books, films and documentaries (yes, cinema was also a passion of mine). 

Two books and three music albums marked strongly my adolescence, some even flagged that embryonic cut from when you become a real adolescent and integrally abandon childhood. This is exactly marked by the moment two very specific events occur in your life almost simultaneously, 1) you start loving someone (or at least at that stage it hurts as if it's love) and 2) you start worrying about the state of the planet and society you have around you. "Zoo Station: The Story of Christiane F." represents a moment in my life as a human being, as a person, where I understood for the first time that some battles had to be fought completely alone, by oneself... and character, resilience and integrity would be pivotal for one's victory. It also alerted me to the dark powers associated to drug consumption. I think parents around the world would help their children so much if this book, or any other pedagogic book of this crude nature became an adolescence gift to raise awareness on the reality of drugs, so much broadcasted these days as cool, entertaining and natural in opposition to their true nature of devastating, criminal and self-limiting substances. The other book was "The Perfume - The story of a Murderer" by Patrick Suskind, a book that actually became the topic for the song 'Scentless Apprentice' by my favourite band ever - Nirvana -, who created my favourite album ever "In Utero". These three icons are deeply embedded in my becoming a Person, the person I am today. The book offered me yet again that misanthropic living that will be life for so many of us throughout our existences, even though the fictional atmosphere is dark, criminal and psychotic, but if we read between the lines there is a person who was born under terrible conditions, never felt loved and spent his life seeking the notion of Love (and self-love) almost desperately with therapeutic objectives, if one can say it. The album offered that same vision but through the eyes of Kurt Cobain, someone I could understand and empathise with so much - my favourite artist ever.

The last two albums that brought up the first adult version of my own self were very different in nature. "The Cult - Pure Cult: for Rockers, Ravers, Lovers, and Sinners" showed me I was starting to feel different whilst reading the world around me, and that that was a genuine interest in girls (one specifically I should say, but that was never corresponded at any time, hence generating that emotional conflict where friendship becomes passion becomes attraction becomes sour!!!!). This album was an awaking moment in my personality for sure. And finally "Chaos AD" by Sepultura who basically x-rayed a world filled with disgust, social injustice and political/societal hypocrisy.

Finally, some people can say Football is also a passion of mine and I have always been naturally good at Sports, but impatient to tolerate what Sports have become as money-making industries. 

My passions were sown inside me in a way that made me a different kid amongst people who were acting really hard to come about Different (as in Cool). But no passion was in me as strong as my love for Science, especially Life Sciences. I am completely addicted to knowledge generated by consuming Science at all times, and that drove me to study so 'hard' in life, and when you do it out of love it's not hard anymore, it's a natural process, a dignifying one, a needed one, a must. I completed my university studies, my BSc, MRes, PhD, worked in research but that passion of mine (Research) was not fulfilled to the most because as a professional route it is deeply rotten and lacking principles and morals. I would not be able to stand for most of the technicalities that define one to be a 'modern slave' of a predefined scripted vicious thinking process, one that nowadays is ever more commercial than actually scientific.

So the way to combine my passion for science with my passion for knowledge and communicating said knowledge was to create a blog. This blog. The blog that shut doors today but that was ever so integral and important in allowing me to suck the juice of having someone interested in what I had to share. The scientific knowledge I was collecting for myself and decided to share with an audience for my questions would definitely be the questions of others. And I did if for quite some time with enormous pleasure and integrity, scientifically and personally, by approaching everything with the due referencing and never assuming absolutism. Everything can be questioned but all questions need a proper thought process. I pretty much enjoyed every single article I wrote hereby and I learned so much with this blog. The Toxicologist Today was, at some point, a flagship of scientific honor for me. The knowledge and debate generated helped solidify that idea that science needs conversational positioning, to attempt to prove or disprove theories.

But times evolve and where I still believe I have so much to give to an audience in terms of scientific communication, something that unfortunately I do not see entirely fulfilled with my professional career due to the limitations associated to the ins and outs of the nature of what I do, ..., I am sure I have so much to speak about, discuss, teach, learn from and debate on. But the platforms are changing, audiovisual channels became a reality of our days and I could see myself deriving to those platforms, but I don't want to. I really could do it naturally, but one thing is missing; that x-factor that really differentiates those who like from those who love, and those who love from those to act upon - The Passion. I don't have it anymore. It is time to seek pleasure in other things as I see myself reading more and learning more but purely for myself. Eventually sharing but not compulsively or needing to, but as a natural occurrence, if it has to be and without any kind of pressure, internal or external.


This is the end of The Toxicologist Today and I thank you deeply for nearly 11 years of my favourite blog on the Web.


Thanks to @Nate_Dumlao for making this photo available freely on @unsplash 🎁 https://unsplash.com/photos/k2GX9kNhXyQ?utm_source=twitter&utm_medium=referral&utm_content=creditShareLink 

Thursday, 19 November 2020

Did you know that ...

 

Altmetric is a tool that allows you to collect and collate research information spread out in the web using a really helpful interface that provides you information on how your own research is seen by others. This is a very useful tool for those scholars who publish, for investigators and even institutions, those who provide grants and those are involved in R&D. Finally a tool that makes all engage in the same platform whilst compiling relevant and useful data on their investigational projects. More information HERE.


Chronic fatigue in Sjogren's syndrome patients - it is known that chronic fatigue in patients dealing with Sjogren's syndrome is probably one of the most invisible debilitating traits of this set of 'diseases'. But a recent article has shed some new light on an agent that interferes with the immunological response and consequently on fatigue, the vagus nerve, that can be used to modulate the immune responses, and with the help of an electronic device, the noninvasive gammaCore. Initial results on a small number of female patients observed positive changes to the profile of fatigue and on the Epworth sleepiness scale (used to diagnose obstructive sleep apnoea) [1]. Reduction in these profiles were also accompanied by significant reduction in the presence of inflammation factors such as IL-6, IL-1β, IP-10, MIP-1α, and TNFα. More information HERE.


Free Resources for Science Pictures - Do you have a blog? Do you participate in a videocast? Are you writing a monograph, essay or any science piece of work that could use some visual attractiveness? Do you need science images but don't really have the money to pay for it. Well, this is the place where you have to go to. This platform suggests 7 places containing high-quality scientific research images that one can access and use at will. From figures, to micrographs, plots and diagrams the images available at the recommended sites will save one hours of unnecessary drawing up. More information HERE.


First Universal Flu Vaccine -  Now that the eyes of the world are layed upon the recent announcement of a vaccine to counteract the sars-cov-2 disease (covid-19), we nearly forgot that there are still numerous 'bugs', prions and viruses out there, roaming at will, looking for an opportunity to prevail. Influenza is just as such one of these and the research for a universal vaccine to prevent flu has been a long standing project. But in 2018 it was announced that the seasonal flu would meet a new defense guard, one that could even protect us against a emerging influenza mutation and avoid a pandemic. Approximately 20 years took these researchers to get to the phase III clinical trial stage where a new complex substance that induces immunity to the less varying parts of the virus (the core of the virus we would say), is to be tested on hundreds, or possibly thousands of human subjects. Knowing that the Influenza virus is made of two surface glycoproteins: hemagglutinin (aiding cellular access to host's moiety), and neuramidase (aiding the spread through), the new pipeline vaccine - BiondVax’s M-001 - will not focus on generating antibodies against the highly variable head of the virus, but instead focusing on producing an immune response against the stalk (a more conserved fragment in the viral structure). In fact, this project is so well advanced and scientifically robust that the researchers are also looking into adjuvants (substances that can aid the primary product work better in an improved fashion). On tof the adjuvants is called TRAC-478 and stimulates several toll-like receptors (TLRs) on antigen-presenting cells; the other one is known as TRAC-478 and can help the body recognise both bacterial and viral infections in a synergistic operation [2]. More information HERE.


The Language of Biosimilars - Have you ever heard of biosimilars? Have you ever been prescribed one? Well, to ignite your responses let us look briefly into what a biosimilar medical product is. A Biosimilar Medical product is a biological medicine considered highly similar to yet another already approved biological medicine (that for that matter is known as the 'reference medicine') and that are approved/licensed with exact the same standards of pharmaceutical quality, safety and efficacy that is applied to all biological medicines. In fact the same agency, meaning the European Medicines Agency (EMA) is the one body, in Europe, responsible for evaluating most of the applications to market biosimilars in the European Union (EU).

The active substances found in biosimilars, meaning the molecules that are indeed expected to do the trick and help cure the problem, are often purified proteins obtained from other living cells or organisms, such as animals, plants, or even smaller ones (microorganisms). The process of protein purification enhances the quality content of the product so the product can be used safely in responding to clinical needs usually related to chronic conditions.  

Confused? Biologic drugs are large, complex proteins, they are 'manufactured' from living cells in extremely complex manufacturing ways; but they are not what we know these days as generics. Roughly said, Generics are 'copy-paste' copies of chemical drugs where as Biosimilars are copies of a biologic medicine that is similar, but not identical, to the original medicine.

Considering that biologics are usually quite large 'protein' molecules with complex structures, biosimilars cannot be considered generic equivalents to these. Instead they are products developed and assessed for their efficacy and safety based on very rigorous processes that study their specific function in different steps of a clinical trial set to confirm similar efficacy and safety. These studies are not performed, or should not naturally be, to show clinical prevalence of these products. [2]


[1] Epworth sleepiness scale - Obstricive Sleep Apnoea (OSA), British Lung Foundation, [https://www.blf.org.uk/support-for-you/obstructive-sleep-apnoea-osa/diagnosis/epworth-sleepiness-scale], last access on the 19th of November 2020, last update on May 2016.

[2] Declerck, P., Danesi, R., Jacobs, I. (2017). "The language of biosimilars: Calrifications, Definitions, And Regulatory Aspects. Drugs, 77, pp. 671-677.

Saturday, 19 September 2020

The science of our days - a post a day!

I've been reading a lot of stuff during this crazy year of 2020, but haven't had the chance to compile and make sense of all the relevant information. I thought of  using the blog to aid me in the task of updating myself on the many levels of scientific information that I've been gathering throughout 2020 (yes, not all is covid-19 in the world, I promise you). 

In that sense and in the coming weeks until the very end of December 2020, I'll be posting a summary a day of quite short (500 words) and straight to the point chronicles addressing a magnitude of different savory scientific topics. 

I leave you with a small list of what is to be discussed and that will definitely entice you all to visit the blog... every single day (starting this Monday the 21st of September so pin it on your calendar):


  • Who’s talking about your research?

  • The Effects of Noninvasive Vagus Nerve Stimulation on Fatigue and Immune Responses in Patients With Primary Sjögren's Syndrome

  • This medication for high blood pressure "increases the risk of lung cancer"

  • Life Sciences Industry Employee Engagement Report 2018

  • Are ketogenic diets really useful in treating cancer?

  • 7 Resources for Free Science Pictures

  • First Universal Flu Vaccine to Enter Phase 3 Trial

  • The promise and peril of gene drives

  • The toxin from a ParDE toxin‐antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti‐gyrase antibiotics

  • Everything is awesome: Don't forget the Lego

  • One million mosquitoes and 500,000 tests later, new buzz about a malaria prevention drug

  • Major breakthrough in quest for cancer vaccine

  • New research: screen time is changing childrens brains

  • PANINI: Pangenome Neighbour Identification for Bacterial Populations

  • Annual Report to the Nation on the Status of Cancer

  • Ranking the 10 Best Survival Kits of 2020

  • 10 Most Dangerous Antibiotic-Resistance Bacteria

  • Recommended composition of influenza virus vaccines for use in the 2019-2020 northern hemisphere influenza season

  • The woman who took on Rockefeller

  • OPAT: Outpatient Parenteral Antimicrobial Therapy

  • What is CAR-T therapy?

  • The Rise of the Scientist Bureaucrat

  • Science Says Drinking Coffee Helps People Slow Aging, Lose Weight, and Cheat Death. These Fascinating Studies Explain Why It's a Miracle Drink

  • Micafungin treatment and eradication of candiduria among hospitalized patients

  • How stress contributes to autoimmunity-lessons from Sjögren's syndrome

  • COVID-19: some unanswered questions

  • How Do Food Manufacturers Calculate the Calorie Count of Packaged Foods?

  • Stress Hormone Causes Epigenetic Changes

  • Decoy antibiotics could get around bacteria’s defences
  • Sugar and cancer – what you need to know

Photo by Clay Banks on Unsplash

111 + covid-19 = a system of 2 that when resolved ends up with lim XY-> +-00

Due to this damn pandemic, family and also professional obligations, it has been increasingly more difficult for me to update the blog. I love the science and the art of writing about science, but I am afraid |to just post for the sake of making numbers as I'd compromise on the quality, and that I despise. Or, I could very simply resort to talking about the same topics everyone else is discerning about, but that would simply go against the purpose of my writing and researching. Finally, I could just jeopardise my professional career and start analysing the absurd verbiage some of the so-said speakers of truth on covid-19 have been confidently chewing all over the news these days; but I do not have the money to support myself nor the 'friends' to back me against the silliness that has been sown so diligently by people who never even studied basic science. One thing I can tell you assertively; I was never a great mathematical genius but good enough to almost finish a biotechnological engineering course. I might not be good but I'm not completely bad. Having said that, I can perform basic calculations and numerical interpretations like the one I propose hereby and that is based on events I personally lived very recently.

A young person is coughing, no high temperature, no persistent cough, a productive one rather than dry, no loss of sense of smell or taste. Keeps munching them baked beans on toast like before and can still identify a strawberry flavored lollipop amidst all green vegetables existing in a not-so-confined-space. So you call the number advised, 111 and add to that a proposed website in order to book a covid-19 test. Covid-19 plus 15 minutes filling up a virtual form results in a system of two equations, the first derives into a drive-through test site (the same one that sent a guy from Kent to Edinburgh for a 7ish hour ride enjoying the tar landscapes of A1) and the other one entails a home test. A simple logical (not so much mathematical at all) observation would expect the common denominator to be... common... in both these system equations, i.e., covid-19 testing. Nothing more and nothing less than the only thing deemed possible for to trace the 'likely' presence/absence of the viral agent. However, there aren't any available tests or availability in the postcode-designated test-sites. If one tries 111 once again one realises that 111 is a number that ends up in formula circularisation, like the ones we mistakenly produce when we get slightly confused when operating calculation spreadsheets, ergo not providing any possible solution but stressing and acting like a headless chicken. One could consider calling 111 once again, thus restarting the formula and wildly attempting application of randomness, envisioning an unexpected successful randomness. But hell no!; the line will advise you to not attempt booking a test via phone and directs one to the very same website that will reinforce you to not call the line as all tests should be booked online. But... but there are no tests, so cone opts in for dying of anxiety or of the disease or utter madness trying to crack this impossible function where:

111 + covid-19 = X + Y with lim X-> +-00 and lim Y-> +-00

Friday, 28 August 2020

What Topic Would You Like To See Discussed Next


Hi everyone, I am finally back from my well-deserved holidays and eager to start posting as much as possible once again. Only this time I'd like to use mine and your time in a much better way, so rather than proposing topics as they come to my knowledge during my work interactions, I would like to see what topics I can help you with.

Bring them to me and I will make my very best to clarify any doubts within my range of knowledge and supported with the best available scientific information out there.

Don't be shy, let me know what would you like to see next on THE TOXICOLOGIST TODAY!

Wednesday, 10 April 2019

Did you know that...

March is over, April is almost half-way done, Mother's Day is long gone now, and maybe over Easter time we can skip some Netflix or Amazon Prime easy entertainment to get our eyes on some very interesting reads. It's never easy to find enough time, I totally understand, but if you love science you always take some minutes to educate yourself. I myself am afflicted by very limited time to check all the science news that emerge daily like a Spring-scented garden. But if from a list of say, 14 interesting links, you pick a single one to really lay your eyes on, you will be automatically more informed than the moment that preceded it.

One single article may provide you with the information that you've been craving concerning that health issue you are affected by, that trick to get rid of fat stains from your new carpet, that medical advance that might be relevant for someone you know, or even that charity that is doing some philanthropic work in an African country that you've always wanted to visit... Who knows?, let the flow of an interesting article entice and seduce you into knowing a bit more science. A learned information cannot be unlearned, it will stay with you forever and one day might be useful.

Find below a list of topics I personally believe are extremely interesting with potential to draw a smile on your face today, for knowledge is not only power, knowledge is also very sexy!

Careers

The 2018 Employee Engagement Report for the Life Sciences Industry is live. Access it to read the 18 pages distilling the relevant information on key motivations and differential, company type, Management and Non-Management, Demographics, Type of contracts and the interesting findings observed. A very interesting reading for anyone on the industry, be it employee, and especially employers.

Environment

The Pacific plastic vortex is being cleaned up by System 001, a gigantic net created by the startup Ocean Cleanup to collect floating plastic from oceanic waters (Portuguese Language only). 

If you would like to know more on the plastic island floating through the pacific vortex read the post published by The Toxicologist Today in 2011.


Lifestyle

And if you're into diets, learn from specialists on how detrimental to one's health can it be the currently famous ketogenic diet (Portuguese language only).


And for those like myself, concerned with animal rights and the lack of options to wear, a great online shop I found for satiating your clothing desires.

Pharmaceuticals

A Universal flu vaccine is entering Phase 3 trial and intends to counteract known limitations of other vaccines against seasonal flu. BiondVax Pharmaceuticals apparently is leading the way towards a great prevention against the 8th leading cause of death that is costing America $87bn.

A new anti-malaria drug in the making; one that might actually be targeting the mosquito parasite at an early stage of life rather than focusing on the reduction of symptomatic impact. A good read with very promising results.


Research

Lego! Your children love eating those colourful plastic bricks at all times. But now a group of paediatricians decided to determine typical transit times for a swallowed Lego figurine head, as a matter of example.

The role of MicroRNA in autoimmunity, with special focus on Sjogren's syndrome, is discussed in this interesting article.

An investigation on whether TNF-like weak inducer of apoptosis (TWEAK) plays a role in cerebral involvement in human systemic lupus erythematosus and primary Sjögren's syndrome with neuropsychiatric implications. 

Discover who is talking about your research by accessing this web page by Altmetric. They track a range of sources to capture and collate activity concerning your publications.

Some researchers are studying the role of the vagus nerve (one of the cranial nerves that has gastric, respiratory and cardiovascular implications in the human body) in fatigue and tiredness in Sjogren's syndrome patients. True or not, the judge is still out there.

If you would like to know more on how I overcame tiredness and fatigue related to my Sjogren's by applying the Wim Hof method, please access this post.

Researchers published pertinent cardiovascular/oncology information in the British Medical Journal concerning the increased risk of lung cancer for those patients taking blood pressure medication, namely ARB and ACEI products (Portuguese language only).


Post image kindly obtained from Motor24, [https://www.motor24.pt/motores/ecologia/projeto-ecologico-ja-comecou-limpar-as-toneladas-plastico-do-oceano-pacifico/?utm_source=ojogo.pt&utm_medium=recomendadas&utm_campaign=afterArticle&_ga=2.151878137.1518736998.1536680189-840951596.1535967158].

Wednesday, 25 July 2018

The ToxicologistToday just contributed to Ava's Journey, can you also add up?



If you follow this blog you've might  have come across some fundraising and donations I have been involved with to help a young child successfully battle cancer (Stage 4 high risk Neuroblastoma). The little one is the 2-year-old daughter (Ava is her beautiful name) of one of my work colleagues, and even though I haven't met any of the involved personally (it's difficult within a global company of more than two thousand employees) I couldn't help but relate deeply to their story (as a father of two and as a person).

For those who don't know much about her disease I decided to transcribe here the words of those that have been involved in her fundraising from the very beginning, in hope that I can at least find one person who can help her reach the appropriate treatment.

"A neuroblastoma is a very rare, very aggressive form of childhood cancer. Sadly, Ava’s cancer is very aggressive also, and it has spread all across her little body. Ava has a primary tumour in her abdomen, located in the adrenal gland above her left kidney. She also has several other tumours in her bones, her bone marrow, as well as in her blood and lymphatic system.

Ava has already started treatment; but she has a very long way to go (approx. 2 years). The hope is after this point she will go into remission…. However; the rates of relapse following remission are high (approx. 75%). Unfortunately, 75% who then relapse, the survival rates are very low second time. But let’s not focus on the negatives; let’s focus on the hope.

Memorial Sloan Kettering hospital in New York have been trialling a drug which has had brilliant results with keeping children cancer free for years longer than before (https://clinicaltrials.gov/ct2/show/NCT00911560) this drug is used on patients who are in remission with Neuroblastoma. Unfortunately, the cost of the treatment is astronomical.

This means that her family need to raise funds to enable Ava to have this treatment. 

No child should ever have to go through this, so if you would like to help in any way it would be truly appreciated.

How can I help, you ask….


Thank you for taking the time to read this". If you need further information access here

Tuesday, 15 May 2018

TheToxicologistToday considered 3rd in the Top 20 Toxicology Blogs on the web

Feedspot, a modern RSS content reader for netizens who want or need to stay up-to-date with the most reliable and interesting content online, have emailed me with special congratulations. It happens that these information minions kindly attributed The Toxicologist Today a third place at the Top 20 Toxicology Blogs (see here). My humble toxicology blog made the podium with a 'bronze medal' that touched my heart, not because of the resonance/repercussion that such might have on my readers' count (if anything that will make me work more seriously towards increasing quality and entice level of my articles), but mostly because someone cared enough to analyse what I have been doing for pure love since August 2010. My small and honest contribution to a world with free scientific information for all - for education and information empower the public. 

Actually, some of the blogs that also made the list are advertised as interesting reads on the side columns of The Toxicologist Today. Some even operate on the realm of Forensic Toxicology, exactly the same area I recently produced a serious game for with SciBoard Games (see here for a short example). This honourable mention, in conjunction with the publishing of my very first digital science serious game "Adna's Lab" (download HERE and read more about it HERE) and the book I am writing on Nosocomial Infections, couldn't be a better bouquet of happiness for me.

I am aware that Feedspot might eventually gain from the fact that all those that made the list will propagate their name to the very four corners of the world (of this worldwide circle squareness), but free information is not easy to maintain or even share. I am more than happy to give Feedspot a hand for their capacity to browse through so many candidates and find value exactly on my work... and with such fierce competition that I am in total awe.


I am humbled, emotional and to a certain degree proud because my scientific passion is surfacing as a valued piece of informational work. I had to read and read and read it over and over again to make sure it wasn't a prank!!!! I thank Feedspot and will do my very best to try and maintain this blog of yours as the reliable source of information on Toxicology that I have been thriving for since 2010. Now go look below for the first 17 names of all blogs that made the top list (I will definitely add all of these links to my 'Interesting Reading column' the moment my professional life allows it).

3. The Toxicologist Today



Wednesday, 21 March 2018

No Blacks, No Jews, No Gipsies, No Children, No Pets

The housing market in the UK has become an issue with no active solutions on sight. And there is only two things to blame: the lacking of political drive and the construction companies backing the lack of political drive (meaning, the lobby). There isn't much to analyse and even though the House of Commons (at least they have a house, poor ones) decided to approach the issue and discuss the very important housing problem in the UK, there is noticeably very little will from the people in power to do things differently and sort this malfunction once for all.

The Members of Parliament sat for hours discussing the housing unavailability and the lack of incentive to build affordable houses, and finally analyse what really promotes the nonexistence of houses and how to tackle the problem, so the present and future generations can have something so basic as a safe place to live.

This political (alleged) initiative is more than welcome, but sitting for hours clapping your members' frigid speeches (from both political arms) to come to the conclusion that:

1) There is a housing problem in the UK, no affordable houses are being built and the current prices are unbearable for the mid-class pockets;

2) There is an emergent epidemics of people sleeping rough, and maybe... just maybe that is also arising from and going to add a few additional points to the housing-problem debate.

Two assumptions any of us could have made without having to belong to any political arm, without having to major in an Oxbridge Campus on degrees that just because they're 'Oxbridgian' will fly you to a very successful career and few concerns about one's future.

However, the real world, the world made of mid-class people who really struggle to afford to pay increasing insane mortgages or rents for houses that arbor many other problems, like the lacking of space - I have never seen in my whole life houses with rooms so tiny as in England that would be called food storage cupboards anywhere else in Europe - or poor construction quality, is here to last.

By the end of my street, in an area known to Nottingham as one of the poorest and more socially complicated, the council is building affordable houses!!!, so affordable that the space takes on the conceptional affordability of the idea and is ever so small. But the prices are not affordable at all, they are £200K a piece and any mid-class family with two kids would struggle to save enough for even initiating the mortgage process. Two blocks away there is another area I don't want to name, but lives on this rhetorical assumption that it is an incredible place to live due to the social fabrics that inhabit it (basically cocky arrogant people with wages well-above the mean who behave like they're the best thing in the world after the invention of the microwave). A 3-bedroom house in this fallacy of heaven costs half a million pounds to buy! Half a million! Super affordable. Anyone can go pick a Neymar Jr. from their bank accounts and personal savings and just pawn their existence like that. Easy!!!

I can understand that the housing issue is now a monster so difficult to resolve that could take longer than a decade to actually see some positive changes. Shared ownership is a fantastic idea, seldom promoted by councils but a great idea indeed. In the meantime, in cities so academic like Nottingham is, the housing market became ever more complicated for families because increasing numbers of students rent basically everywhere, houses that accommodate many people but are framed and shaped for quick occupancy. Not a legacy for the future with family and familiar environments. When looking for a house to rent, like we as a family have been doing for about 5 years now, you have narrow options and must accept conditions you wouldn't normally accept for the fact that if you do not want to live under such conditions, you won't have a place to live at all. There is a queue waiting for those four walls with a roof on top and the landlords are thriving on this market. 

A month ago we visited a house in that same complicated area of Nottingham that I referred to, above. One with mold everywhere, rusty pipes, lacking space for a normal living and there was humidity and holes (serious holes) on the ceiling - £700 they asked for a place that shouldn't be charging more than $400-£450 considering the area and the quality.

I'm not even mentioning London, that is a bubble on itself obeying to much stricter/ridiculous conditions. This is East Midlands where people still want to live in normal, acceptable, safe, affordable houses. Not zoo cages!

Landlords got to a point where they can demand obnoxious things fully accepted by the regulators. Things embedded in such prejudice that any normal government would determine these as unlawful and criminal. The last agency we contacted didn't even book us a house viewing because the landlord clearly stated he wanted No Children. The moment we said we were a family of working parents with money to pay the monthly rent, this person 'cryed' No Children allowed in the house. Like if he was talking about some family of wild boars with cubs ready to destroy a house the moment they were granted access. Like if he wasn't protected by a deposit safeguarding scheme and a contract that makes tenants responsible for any damage on the property. The reason for that is just quick quid, making money easy on students and making sure that the house is for a tenant-in tenant-out system whilst collecting deposits based on some ridiculous structural assumptions. I know what I am saying as I had to 'battle' my share of rogue landlords and their greedy claims when I was a student myself.

If the local councils and even the national government allow such 'legal' prejudice we will return to wild times where landlords could clearly and lawfully announce on their property doors "No Blacks, No Jews, No Gipsies, No Children, No Pets". Can anyone else see the incredible prejudice that is emerging once again from a problem that is itself a prejudice against the mid-class people? Can this be more blatant than what it already is?


Thursday, 1 March 2018

Status of EU citizens in the UK: what you need to know



Information for European Union citizens living in the UK.



Published 7 April 2017
Last updated 28 February 2018 — see all updates